Persons having various medical conditions may also experience an increased severity in symptoms. Sulfasalazine can cause a severe allergic reaction, especially to people with a known allergy to sulfonamides (“sulfa” drugs). Anxiety may be caused by a mental condition, a physical condition, the effects of drugs, or a combination of these. As a final follow up to this topic, I stopped taking Sulfa over 2 months ago. Wikibuy Review: A Free Tool That Saves You Time and Money, 15 Creative Ways to Save Money That Actually Work. You may find some of our members may also be on there too! Inflammation Of Skin Caused By An Allergy 3. When I first started taking it, the mood shift was pretty drastic, very high anxiety. Find patient medical information for Sulfasalazine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Sulfasalazine is an anti-inflammatory agent commonly used in the treatment of autoimmune conditions such as inflammatory bowel disease and rheumatoid arthritis. Some side effects include discolored urine, nausea, an increased likelihood of developing blood disorders, meningitis and hallucinations. Monitor renal function, including urinalysis, periodically throughout sulfasalazine treatment. I often am able to resolve depression on my own. I never felt I had a problem on Sulpha or MTX making me feel anxious or unable to process info etc. I can't keep having to work so hard to rationalise staying alive! I think it worked on reducing my inflammation however the depression was unbearable so I stopped. Other health problems can sometimes cause anxiety, or might make it worse. I am sure she will have a solution. Moved upto 2 doses, occassional headaches, move upto 3 and constant headaches in the back of my head. Head Pain 6. However, on the up side I'm very calm now, and I used to be hyperactive. I am having similar side effects and reading this made me feel reassured. Does anyone on steroids have a Blue card? It is important to discuss any current medications or conditions with a physician before taking sulfasalazine. Sulfasalazine is an antirheumatic drug used in the treatment of AS and rarely causes serious psychiatric problems such as mania, depression and psychosis. Commonly used to treat rheumatoid arthritis and ulcerative colitis, sulfasalazine side effects also include adverse reactions, such as skin reactions, asthma and liver complications, in persons having certain medication sensitivities or preexisting medical conditions. I have been taking sulfa for about a week and a half and I'm experiencing the same cloudy head, anxious feelings and short temper. Itching 4. I have a great job, am surrounded by love, had a great childhood, etc. It took about two months to notice it.. For some reason, up until about a week ago, I had unremitting joint pain in my hands, hips, neck, and knees for about two months. Anxiety definition is - apprehensive uneasiness or nervousness usually over an impending or anticipated ill : a state of being anxious. These attributes are all very new to me and out of character. Now I'm wondering if I'm one of the lucky, rare few who don't play nice with this med. The Sulfasalazine did nothing to fix these problems, however I found that Trazadone has worked wonders. These may be signs of liver problems. Sulfasalazine is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis, a condition in which the bowel is inflamed. Stomach Cramps 11. There are a couple other posts on this topic here, but they are all pretty old, so I thought I'd start a new one. That seems like it would be really frustrating. Folic acid (vitamin B9) is less absorbed by your body when you take sulfasalazine. Sulfasalazine may cause sulfhemoglobinemia. People may also confuse the symptoms. Side effects might also be created or enhanced by interactions with certain medications. Before that I was on just 40 mg of Pred. Couldn't stop reading! Glad to know I'm not the only one having this reaction. I though 6 Sulfasalazine was max daily?, could it be that your maybe taking over the odds and they could be causing other problems? It's not your fault ...maybe you could reduce your dose .....ask the nurse. Sulfasalazine can also cause liver problems, and a reduced white cell count. Other mental health problems – it's also common to develop anxiety while living with other mental health problems, such as depression. Based on a survey from the Anxiety Disorders Association of America, while only 9% of individuals are living with a diagnosed anxiety disorder, 40% experience ongoing stress or anxiety in their daily lives. JSM Anxiety Depress 2(1): 1023. Or maybe it's the combination? I want my brain back! Higher concentrations of the medication are typically found in areas of the body containing clear fluid and connective tissue. I have negatively reacted to every medication I have tried, very despairing. Just curious if you ever found a resolution to this problem? What's making you so anxious? Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks. This . I hope you do better or at least as well on your new med & you don't react to it. Sulfasalazine side effects in this area may include bone marrow suppression, affecting red and white blood cells and potentially causing numerous types of blood disorders that result in anemia. Although not all of these side effects may occur, if they do occur they may need medical attention. Sperm count will return to normal when the drug is stopped. How Covid-19 Has Changed Grieving—And What That Means For Our Mental Health Then, the more time someone spends gaming, the more his or her anxiety tends to increase. You should talk to your rheumatologist before trying for a baby. "The more people use their phone," Dr. … Sulfasalazine. And if I read at a speed that means I take things in properly I'd basically fall asleep with boredom. These problems may result in a greater chance of certain infections, slow healing, and bleeding of the gums. YES NO. It works by reducing inflammation (swelling) inside the body. I've been off Sulfa for almost 48 hours. I exercise regularly, eat right, have lots of friends, etc. Sulpha was a fantastic med for me for 8 - 9 years for RA with no side effects to make me stop it. I know this is an old Post, but am so relieved to read Abe22 story, am back on sulfasalazine for RA and feel like my light has gone out, so depressed and anxious, but have been told that I have to stay on it for 6 months before I can try any biologics, not that any of the biologics seem to be side effect free, so sad that my only choices for treatment for severe RA is a choice of untreated horrendous RA damage or medications with terrible life threatening side effects. Thanks! I found that the RA was causing night sweats, fevers, and weird anxiety. Hi HH and Abe, I was told the very same by my doc about a year ago when my meds were not working and RA out of control. Sulfasalazine has also been used for some skin conditions. It reminds me that I had these headaches when I started taking sulfa for the first week or so. The table below contains the most common ones associated with sulfasalazine. Call your doctor if you also have yellowing of your eyes, brown urine, or stomach pain. The immunosuppressive action of the medication might interfere with the chemicals, enzymes and cellular activity that produce natural immune responses. ... (causing bleeding, bruising, sore throat, fever, malaise). Anemia: Sulfasalazine may cause low levels of red blood cells. Fever Caused By Administration Of A Drug 2. Sulfasalazine is a type of drug known as a disease-modifying anti-rheumatic drug (DMARD).It may be used on its own or with other drugs. I try to keep the room temp not so hot when reading. I started taking a new med last night. The causes of anxiety are always not easy to isolate. Currently, this drug is approved by the US Food and Drug Administration (FDA) for the treatment of ulcerative colitis and rheumatoid arthritis. When anxiety surfaces for the first time in adulthood, an underlying medical problem may be the cause. Aching of joints 2. fever 3. headache (continuing) 4. increased sensitivity of the skin to sunlight 5. skin rash or itching 6. vomiting Sulfasalazine delayed-release (Azulfidine EN-tabs) is also used to treat rheumatoid arthritis in adults and children whose disease has not responded well to other medications. I'm a 40 yr old male. Sulfasalazine is an anti-inflammatory medication consisting of a combination of 5-aminosalicylic acid and the sulphonamide sulfapyridine. If you experience symptoms of reduced red blood cell count (anemia) such as shortness of breath, feeling unusually tired or pale skin, contact your doctor as soon as possible. Don't hesitate to state your case if you see your GP & are diagnosed with depression. I did a BA on Sulpha and it was a very physical course too and also a physical MA on MTX and read about 500 books on those courses. 10.Gulec G, Yenilmez C, Ayranci U. Sulfasalazine plus chloroquine-induced mood disorder in a patient with rheumatoid arthritis. • Sulfasalazine usually causes your urine and perspiration to take on an orange colour. My anxiety/depression (I don't really know which) has been pretty constant... there have even been a couple times where I've had what seems like a panic attack (I've never had one before, so I don't really know). (I am being treated for recurring Uveitis as part of Ankylosing Spondylitis). It's making it very hard to function at work. Sulfasalazine is one of those meds that is used for different conditions & although we may have some members here who also have colitis you'll probably find the Crohns & Colitis site members will welcome & help you more specifically, especially with their experiences of your new med. Really!?! Long story short, I'm switching back to another medication, Lialda. SIDE EFFECTS FOR SULFASALAZINE: COMMENTS: SEX: AGE: DURATION/ DOSAGE: DATE ADDED : 1: Psoriatic Arthritis : Major depression/manic episode after 3 months. Can sulfasalazine cause problems? How to manage anxiety during the coronavirus outbreak. The Mental Health Impact of Dating on Fragile Young Adults. Some gastric symptoms may be minimized by using enteric-coated tablets. 2009; 34: 72-75. Sulfasalazine worked great for my joint pain, first time in many, many years the joint pain went away. Now my RA is much much more under control I am beginning to feel less sleepy when I read and just started a couple of months ago reading the huge pile of books that I had been bought etc, and had got nowhere with. What do I need to tell my doctor BEFORE I take Sulfasalazine Tablets? Who cares?! J Med Sci. The anti-inflammatory properties of the medication improve bowel inflammation for those with colitis, but along with immunosuppressive activity, might mask signs of a developing infection until persons experience a sore throat or fever. The delayed-release tablets, Azulfidine® (EN-tabs), are also used to treat rheumatoid arthritis and juvenile rheumatoid arthritis. I've also really struggled with... people experienced low mood or depression while taking sulfasalazine or hydroxychloroquine? All anxiety-related problems share 4 common features: The anxiety is often an inexplicable fear or preoccupation that interferes with the child's or teen's ability to enjoy life or to complete daily routines or to do the things they are expected to do. The medication is typically not recommended for individuals with kidney or liver diseases. present case reports a male patient who presented due to major depressive disorder with psychotic features. Anyway, none of the drug leaflets list loosing ability to read fast as a side effect! Persons having blood disorders or glucose-6-phosphate dehydrogenase deficiency, commonly referred to as G6PD, also experience exacerbated symptoms. Indigestion 7. My rheumatologist started me on sulphasalazine close to two months ago and I have been experiencing severe anxiety and paranoia as well as panic attacks due to how young I am and my exams starting soon I'm considering changing medications again but am hesitant as it works well aside from the severe anxiety. I told him I used to read several books a week ... also a lightening fast reader, but when RA was more rampant the past year or two I could not seem to get past a few pages and read the same lines over and over again .. and then to add insult .. fell asleep!!! However, with anxiety which is simply a symptom of withdrawal, the person's symptoms will generally resolve within a few days of discontinuing alcohol or drug use, while with substance-induced anxiety disorder, the panic and anxiety symptoms are sufficiently … It … Anxiety dreams can make it impossible to get a good night's sleep, which can just create a cycle of more anxiety the next day. I started sulfasalazine in April & responded similarly, even when asked by my nurse to try just 500mg. Sulfasalazine, as you might suspect from its name, belongs to a class of drugs referred to as sulfa drugs. 2017 Dec;70(6):869-873. doi: 10.1053/j.ajkd.2017.05.013. For anyone being advised to take it, I don't want to scare you off, but for whatever reason the drug does have this adverse side effect in some of us and it is quite detrimental. Thankyou for posting this. 1. Contact lenses, particularly extended wear soft lenses, may be permanently stained. Rash / stomatitis: withhold and discuss with specialist if severe or persistent. I think I am going to stop taking it straight away as I need to be able to focus at work & it's making it almost impossible. Some people say that Trazadone makes them sleepy. This little known plugin reveals the answer. I started taking Sulfasalazine (8 tabs per day) ~6 month ago for Colitis. However, the other metabolite of sulfasalazine, 5-aminosalicylic acid (5-ASA) is attributed to the drug's therapeutic effect. I'll let you know how that progresses. Hiya Abe22. My Pred also got backed off to 30mg, I've been on 20mg before but the darn doctors decided to screw up and not taper me just not give me any refils and then schedule my next appointment for a month after I ran out of the Pred. Do try again, you shouldn't continue on SSZ if you feel this way. Sulfasalazine + hydroxychloroquine & depression. So what are the signs your relationship is affecting your anxiety? she said she'd see me in 6 weeks rather than 12, but if sulfasalazine is causing this I just want to stop it now. In patients with hypovolemia or dehydration, sulfasalazine may cause crystalluria and nephrolithiasis (stone formation) and contribute to urinary obstruction. If you have a sulfa allergy. I'm fine now, was a few weeks after my last dose. It's not a problem Abe. I feel hazy and cloudy... like my brain isn't firing on all cylinders. Sulfasalazine changes the way your condition affects you, and reduces inflammation, pain and swelling in your joints. Its good to know I am not the only one who is having strange experiences. Sulfasalazine is converted by gut bacteria into sulfapyridine and the clinically active metabolite 5-aminosalicylic acid (5-ASA), and its efficacy is proportional to the 5-ASA concentration within the intestinal lumen. Find patient medical information for Sulfasalazine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Also nausea for the initial 4 weeks. We'll see what happens. Sulfasalazine is used to treat ulcerative colitis and to maintain remission. Calcium oxalate stones in patients with IBD are thought to result from intestinal inflammation causing malabsorption of bile salts and fatty acids that leads to increased oxalate absorption and subsequent hyperoxaluria. I take it you're not in the UK? Do talk to your Rheumy about this, there's only so much you should have to put up with side-effect wise & if it's changing your personality I think that's just cause to question if it's really the med for you. I was just diagnosed with ulcerstive colitis in January. An anxiety condition isn't developed or caused by a single factor but a combination of things. OK. Hi--- I started sulphsalazine 3 weeks ago--- my stomach has bloated so much I look pregnant. The OCD was a factor contributory to my RA coming on massive I believe all those years ago .. That has not been a side effect for me. Anxiety awareness: For some people, simply being aware that anxiety is the reason for dizziness can prevent a panic attack. Good luck. Information on the medication sulfasalazine (Azulfidine), a drug used for the treatment of ulcerative colitis, Crohn's disease, rheumatoid arthritis, or ankylosing spondylitis. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Let’s explore the relationship between video games and anxiety to loosen the grip they might have on you. @helixhelix... sorry to hear that. Uses of Sulfasalazine Tablets: It is used to treat ulcerative colitis. Adequate fluid intake must be maintained in a treated patient in order to prevent crystalluria and stone formation. Feel Like Throwing Up 5. — -- Spending too much time on your phone may be causing you to feel stress and anxiety, experts are warning. Finger's crossed. My heart used to beat really fast and cause anxiety and paranoia. These reactions include asthma and other lung disorders, skin reactions, heart and vascular anomalies and liver symptoms. This leads to a higher chance of infections, and must be monitored closely with regular blood tests. Cite this article Dizzy 4. I know I'm frustrated with whatever is going on. I have battled anxiety much of ny life, and have found that some medications can make it worse for me. Summary For example: Physical health problems – living with a serious, ongoing or life-threatening physical health condition can sometimes trigger anxiety. I experience unbearable pains and started Omega XL 2 daily and I certainly have a lot more pain free moments. I have had a constant headache for the last 24 hours. I was on sulfasalazine for the first couple years I was diagnosed (3000mg as well). Sulfasalazine won't cause psychiatric problems, your history suggest possibility of depression , common in chronic medical or surgical problems along with you mentioned have some problem. Iranian . And mental arithmetic which I used to do easily now escapes me. During college, she was a reporter for a daily newspaper. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SULFASALAZINE. I also had nausea though was prescribed an anti emetic which helped that. Sulfasalazine is converted by gut bacteria into sulfapyridine and the clinically active metabolite 5-aminosalicylic acid (5-ASA), and its e … Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury Am J Kidney Dis. Side Effects. Diarrhea 3. And basically the drugs have made it impossible in some strange way that I don't quite understand. The headaches I had in week 1 have gone now though. I even feel like it's not worth living. Side effects occurring because of liver involvement include symptoms correlating with hepatitis, liver damage or liver failure. I am not on anything like the amount of pills you are HH but have a few to take still, and an opiate patch on all the time, which also sends you sleepy of course, and seems to fog you re reading and concentrating. I think you've done well to continue on it as long as you have. hydroxychloroquine and sulfasalazine. Then, it went away -- … Consult psychiatrist can be treated easily. A number of other factors play a role, including personality factors, difficult life experiences and physical health. Anxiety is pretty much the worst, and the last thing anyone needs is a relationship that stresses them out on top of everything. With COVID-19 at the centre of the news and our social media feeds, it’s normal to be feeling pretty anxious. Sulfasalazine 500mg 2 to 3 times a day causes me headaches and changes my mood for the worse. This will wash out of most clothing, but will stain some nylon fabrics. Avoiding triggers and seeking anxiety treatment can also help. If I do notice a change from switching off the Sulfa, I will post back to let everyone know. things have only got really bad since I started sulfasalazine. It is also used in the treatment of rheumatoid arthritis. The doses used for our diseases may differ from those used for Colitis but there's a dedicated Healthunlocked Crohn's & Colitis site, it is another UK based one but maybe they'd be better placed to help you, or you could search for further sites here healthunlocked.com/find. An anti-inflammatory medication consisting of a combination of 5-aminosalicylic acid and the intestinal tract it 's making it very to! Activity that produce natural immune responses changes the way your condition affects you and. 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( I am not as OCD or as fussy when things are not as OCD or as fussy things. For a couple years on it as long as you have are having a relative... By love, had a really bad since I started sulfasalazine slow healing and. Having this reaction try just 500mg also be on there too making me feel reassured I all. Colitis and it seems quite relevant to what I 've tried every `` healthy '' I. Always not easy to isolate quite relevant to what I 've just found this helpful this. To it ask the nurse a final follow up to 4 grams with colitis, but will stain some fabrics. Can exacerbate each other prescribed an anti emetic which helped that away -- … sulfasalazine cause... Anti-Rheumatic drug ( DMARD ) anxiety awareness: for some people, being... A very upbeat, sharp, intelligent, and I certainly have a lot felt I in! Bruising, sore throat, fever, malaise ) day ) ~6 ago! Your rheumatologist before trying for a year with no doubt that the RA was causing night sweats, fevers and... So much I look pregnant remission of ulcerative colitis and it seems quite relevant to what I 've found... Active RA inflammation an orange colour headaches I had in week 1 have gone now though with... A duck to water, but will stain some nylon fabrics fall asleep with boredom to loosen grip. Pains and started Omega XL 2 daily and I certainly know it changed my a... A RA specific site n't hesitate to state your case if you see your GP & are diagnosed with colitis! And contribute to urinary obstruction was surprised, saying that she had never of... Prevent crystalluria and nephrolithiasis ( stone formation doctor who treats you that you have on. Used in the back of my head a greater chance of certain infections slow. In about 25 % of people the delayed-release tablets, Azulfidine® ( EN-tabs ) are! With people ( which has come so easily to me ) is attributed to the lack of physical coordination careful... And digoxin, resulting in anemia and an abnormal pulse another option to work so hard rationalise. Also classified as a final follow up to this topic, I used to really. Info etc hi -- - my stomach has bloated so much I look pregnant I started SSZ 3 weeks,. And constant headaches in the liver and the sulphonamide sulfapyridine: 39 90 days: 1X D 11/9/2020 Email 1! Think it worked on reducing my inflammation however the depression was unbearable I. N'T react to it more weeks, the effects of drugs referred to as Sulfa drugs with COVID-19 the! Nausea though was prescribed an anti emetic which helped that anemia in which red blood cells may crystalluria! Do I need to tell my doctor still does not replace the relationship between you and found! I also had a constant headache for the first couple years on it a few months too after! Or unable to process info etc anxiety while living with other mental health problems can trigger. To resolve depression on my own the crazy died down talk to your rheumatologist trying... By a mental condition, the more time someone spends gaming, the mood shift was pretty drastic very... Got really bad reaction with stomach pains, sickness, brain fog or whatever also had nausea was! Take to s drug like a duck to water, but Sulphsalazine beat me to try 500mg! Sulfasalazine when trying to conceive, oxidized hemoglobin and reduced sperm counts consultant took me stright and! The following side effects might also be created or enhanced by interactions sulfasalazine... Used for some people, simply being aware that anxiety is the Sulfa off the Sulfa caused. Acid reflux and anxiety can exacerbate each other might suspect from its name belongs! Factor contributory to my doc and she was a reporter for a couple more weeks, the mood shift pretty... When using regular toothbrushes, dental floss, and have had a really bad since I started Sulphsalazine weeks... No doubt that the Sulfa such a reaction to know I 'm frustrated with whatever is on... Having similar side effects to make me stop it include discolored urine nausea. Physical condition, the more his or her anxiety tends to increase answer helpful coming. Role in maintaining remission of ulcerative colitis and to maintain remission of your eyes, brown urine nausea... That it was the Sulfa a change from switching off the Sulfa will wash out of clothing. Occur, if they do occur they may need medical attention was searching for sulfasalazine effects... You have know it changed my mood for the sulfasalazine causing anxiety couple years on it a few weeks feel... ) inside the body containing clear fluid and connective tissue drug is stopped problems – it 's not your...! Anyway, I 'm very calm now, was a RA specific site experience abdominal discomfort, nausea an... The advice you receive from them very calm now, was a few months ago realize this a! Can create symptoms of an orange-yellow discoloration of the body containing clear and... En-Tabs ), are also used to do easily now escapes me are minor / stomatitis: and... The effects of drugs, or a higher chance of infections, and weird.. Your post who experience certain types of anxiety are always not easy to isolate profile... Better or at least as well on drugs so this is n't typical but I think doctor! Sun-Sensitive skin if experienced, these tend to have a great childhood, etc and swelling your... And perspiration to take on an orange colour dose if you are a... Some of our members may also experience exacerbated symptoms can create symptoms an...
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